Photoshop crashes every xx minutes when working with large files – unusable

Does turning off »Use Graphics Processor« in the Performance Preferences (Photoshop > Preferences > Performance > Graphic Processor Settings) and restarting Photoshop have any bearing on the issue?

Well the immediate reason for the crash is a memory fault, may be Photoshop accessing memory somewhere that has not been allocated to Photoshop beforehand. As you say that this happens on big images it could be a could guess to blame memory management in a stress situation (either MacOS or Photoshop).

A test to do is to run Photoshop alone with minimal background activity.

I suppose that Netflix and Photoshop both use graphics resources quite extensively, so that may cause the system crashing because a graphics driver issue.

You did not state what a larger file means for you. But that could be a very important information here for the Mac specialists.

Did you send in the report?

What have you done for trouble-shooting so far?

Restoring Preferences after making sure all customized presets like Actions, Patterns, Brushes etc. have been saved might be a good starting point:

https://helpx.adobe.com/photoshop/kb/basic-trouble-shooting-steps.html

Moved from  Adobe Creative Cloud​ to Photoshop

Well, here are a few questions first. What else were you running at the time? Seems like you had a few other things going on when this error report came down. Possibly even some game running in the background? Since a game controller came up in the list, I'm guessing you might have a game or two on there...

Also, you have 27 devices plugged into your computer at once via USB. Were they all active and being used? Or could some of those be shut down while you are actually working? Your computer only has 16gb of RAM, and with too much going on in the computer, that 16GB could get eaten up pretty quickly. And Photoshop is definitely a RAM pig. Especially with large files. Try not running anything else on the computer while you are working on it as well as shutting down as many of those peripheral devices. It is only a laptop, not a big workstation, so minimizing the load while working is a something you need to think about.