workspace and interface

​@AlexColvin As in the actually interface where you can make it transparent? Then short is no. 
 

It sounds like a little more clarification might be needed, as to what kind of workspace transparency you need compared to what’s already offered in Photoshop. Because initially, talking about workspace transparency suggests the ways described below in which Photoshop handles document transparency, but maybe you have something else in mind?

First, if the Layers panel shows a bottom layer named “Background” with a lock icon, that Background layer is an opaque background for the entire document. If you want a document to have a transparent background, the Background layer must be deleted (which you can do if the document has at least one other layer), or you can unlock the Background layer and erase any part of it to transparency.

Or, are you wanting to control how fully transparent pixels appear in the workspace? By default, if pixels are fully transparent, by default Photoshop displays a gray checkerboard pattern. You can customize the size and color of the transparency indicator grid squares, as shown in the picture below. The reason this is important is so that someone can tell the difference between a pixel that is white (RGB 255,255,255) and transparent (not white, but completely clear). 

Or, did you want to create a preset that always creates a new document with a transparent background? To set that up, in the New Document dialog box, click the Background Contents menu, and choosing Transparent; then saving all current settings in the dialog box as a named preset at the top. 

Does any of this help, or are you thinking of “transparency” in a different sense? Because it sounds like what you need to do is more clearly see edge artifacts? That sounds like it might be a different meaning of transparency than the way we think of that term in Photoshop.

For example, if the problem is not being able to clearly see edge pixels that are almost but not quite fully white or black, there are methods that can help make those easier to see, such as a temporary Threshold adjustment layer or Stroke layer style.