Disabling a Signature Field based on a check box being selected

I have a PDF form where operators have to select a checkbox based on a desision. Then apply the signature next to the check box they have created. The application of the signature locks off fields further on in the form as required. 

Is there any way I can make the apposing signature box unavailable based on the selection of the check box. For example, if 'FILL ON TOP' checkbox is selected, the signature field for 'NOT FILL ON TOP' becomes unavailable / locked?

Thanks 🙂