Hi patrickg54,
As you are trying to print PDF in an 11 x 4.25 layout, first you need to customise the paper size.
Please refer the steps provide below with the screenshots:
- Open the PDF file and click on Print icon.
- Select the printer from the list in the print dialogue box and click on Properties tab.

- Go to Paper/Quality and under Paper size click on Custom > New.

- Now name the custom paper size as per your wish. Then change the Width to 4.25 & length to 11.00.

- Click on "Add" and then "OK" to save settings.
- Now, check if the customise size is selected under Paper options on printer properties window and then click "OK" below on that page
- After selecting the paper size, click on Multiple tab under Page sizing & Handling and select the number of pages from the drop down for Page per sheet.
- Then select the Portrait/Landscape under orientation as per your requirement.

- Now try to print the file and check if the output is as required.
Let us know if you need any help.
Regards,
Meenakshi