Opening a new pdf adobe will open in a different desktop

Hi @francesco_5687, 

Sorry for the delayed response and for the troubled experience. 

Try the following steps: 

There are no preference settings to set the default screen to open a document.

To open the application on the main screen, please try the steps provided below:

• Open Adobe Acrobat Reader DC and resize the window.
• Move it to the main screen and close it.
• Now open the application again and maximize the window.
• Then close it.

Now check if it opens by default on the main screen.

For a similar discussion, please visit this thread: https://adobe.ly/4h0jArc

Thank you for your continued patience and understanding.