How to make shortcut keys.

The answer is no.
This is a feature that users have been requesting for over 20 years, but Adobe remains unresponsive.

Hi Snow,

Thanks for reaching out. As described above, you want to create the shortcut keys for Adobe Acrobat/reader, correct?

We have predefined set of shortcut keys for Adobe Acrobat/Reader for Windows as well as Mac OS. To enable single-key shortcuts, open the Preferences dialog box (Edit > Preferences), and under General, select the Use Single-Key Accelerators To Access Tools option. For detailed information about the shortcut keys please use the help article - https://helpx.adobe.com/in/acrobat/using/keyboard-shortcuts.html

Hope this helps

Regards

Amal