Although PDF provides a forms capability with some built-in mathematical capabilities and with some custom JavaScript, you can emulate some aspects of a spreadsheet.
Neither Excel's built-in Save as PDF nor the Acrobat PDFMaker Save as Adobe PDF option even attempt to translate the Excel spreadsheet content into PDF forms since so much of that spreadsheet functionality is not part of PDF forms.
The fact is that if what you want is full spreadsheet functionality to be available to the recipients of your document, send them the Excel spreadsheet or alternatively create a PDF file using Acrobat PDFMaker Save as Adobe PDF and specify the option to attach the original spreadsheet inside the PDF file for use of the recipients who wish to play with numbers.
- Dov