I work at a tech company and our client has this issue and the funny thing is this only happens on 2 of their computers. All of the computers are W10 Pro,16GB Ram, I7 Cpu's, Adobe Acrobat Pro fully updated. I have tried almost everything possible. Updating graphics drivers, rolling back graphics driver. Updating BIOS, windows updates. Every other computer that opens large AutoCAD files works fine. When you try to open on 2 of the 10 computers after scrolling for a couple of minutes the whole window freezes up and you have to force quit. When I contact adobe through chat they are absolutely useless and tell me to "repair" the file and try simple troubleshooting steps that we have obviously tried already.
They are getting super frustrated because from a buisness standpoint it is absolutely unacceptable for the program you are paying for cause this much grief.
Adobe if you are reading this. DO SOMETHING.
I'm not sure if this works for Windows, but on Mac I'm having success by unchecking Preferences / Accessibility / Enable assistive technology support.