Set default print settings to a PDF

This is indeed a printer driver thing.

However:

Create a Portfolio PDF out of 4 separate files for page 1, page 2-3, page 4 and page 5.

So when they are printed (double-sided), each one is printed as a separate job. The single ones should come out with a blank back side.

A second more jerry-rigged way is to insert blank pages into your single file (i.e. 1-blank-2-3-4-blank-5-blank) 😉

@gregb94621243 I'm not an expert on this and maybe others will chime in, but as far as I know, you'll need a printer that supports switching the printing mode from simplex to duplex and back in mid-job. I don't think this is a capability that Acrobat provides within the software. It's something you are going to have to set in the printer's settings on export. There may be an efficient way through a script that automates first printing all the single pages (1,4-5) and then printing the double-sided pages (2-3). You would then have to collate the sets after printing.