The application “Adobe Acrobat.app” can’t be opened.

In my case, Acrobat was in the middle of an update. However, it didn't give any hint that was the case. When I tried to shutdown, a dialog appeared letting me know what was happening. Once the update completed, everything was back to normal.

Hello @GottaRun 

I hope you're doing well, and sorry for the trouble.

Please try to remove the application using the cleaner tool (Acrobat cleaner tool)  and reinstall the application using this link:

https://www.adobe.com/acrobat/acrobat-pro.html

For testing purposes: Please try to turn off the protected mode and see if that makes any difference. Go to Adobe Acrobat > Preferences > Enhanced Security > Uncheck 'Enable protected mode at startup,' turn off the protected mode and uncheck the enhanced security > Click OK and reboot the computer.

Note: Turning off the security may contain security risks; please turn on the security after testing.

Let us know how it goes.

Regards,

Krutikka