Adobe Reader Error - Cannot open application

When attempting to open a .pdf using Adobe Reader, I get the following error on one PC only (at this stage).

I've attempted to uninstall and re-install Adobe Reader but the same issue occurs once re-installed. I've followed all steps from the https://helpx.adobe.com/acrobat/kb/fix-acrobat-crash-on-launch.html none of which helped.

Is there something in the register that I can delete after uninstalling the program, so that we I re-install again, it's a clean install?

Any assistance here would be great. Thanks