Audition won't start, may be due to temp file location being gone

I have Audition CS5.5 installed on this computer. When I try to open the program I get a message: the program has asked Runtime to terminate it in an unusual way. Can anyone suggest a fix for this problem. I understand that it stems from a choice made of where to save temporary files and that location being no longer available, but if I can't open the program there is no way to get in and choose another location!

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