Hi Scott,
We are investigating the issue extensively which has been introduced as part of latest flash player update.
However, if it is really urgent for you i can suggest you some workarounds:
1. If you play the SWF content from a server instead of playing it locally, it will work fine for you. You can play it from a web server or a wamp server etc.
2. If in case you do not want to go with above workaround, here is another one: Press Windows key +R and type in %appdata% and hit enter key. Go to the folder " ........\appdata\Roaming\Macromedia\Flash Player\#Security\FlashPlayerTrust" and open the file named as "TalkToAdobeFlashPlayerTrust.cfg" and add the location of your Presenter publish output folder and save the file in same location.
For eg. in my case i added this entry- "C:\Users\zhussain\Documents\My Adobe Presentations". Once you have done the change to this file, you will be able to play your SWF output locally in Internet Explorer and Firefox. Remember this will still not work for Chrome browser.
kindly let me know if you need any further help.
Regards,
Zeeshan