Issues when saving a file using latest update of Illustrator 2022

  This happened in the past., and not to everyone.

I can give you a dozen suggestions from a thorough cleanse of your  prefs, removing recently installed fonts, cleansing your font cache,  to restarting your computer, but please provide more information such as your OS, OS & Ilustrator plug ins, screenshto of your art, notes on creation of art and how many other files this happens to,  when posting and you will get a better reponse

Hello @b squires,

Sorry to hear about this experience. Are you facing this problem with other files as well? If yes, kindly try resetting Illustrator's preferences by following the steps shared in this article (https://helpx.adobe.com/illustrator/kb/troubleshoot-preference-issues.html) and sharing your observations.
Disclaimer: Please note that resetting preferences will remove all custom settings, and Illustrator will launch with the defaults. You may take a backup of these settings from the location mentioned in the article.

Looking forward to hearing from you.

Thanks,
Anubhav