removing guides doesn't seem to be working

Here is a template from Vistaprint that I am trying to work with. It says to remove guides before saving. My understanding is that you remove them by going to View, Guides, Clear Guides. I have done that and I can still see the red and blue bleed and trim lines. I also tried deleting them in Layers panel.

I don't work with Illustrator much at all so perhaps I am not doing this correctly.

The reason I ask is that I sent Vistaprint something on which I thought I had removed the guides--but they showed up on the preview for the document.

Thanks!

EDIT: Here is the image.