SHIFT ALT OPTION keys not working in Adobe.

There is a bug request about this at UserVoice: http://illustrator.uservoice.com/forums/601447/suggestions/47354918

Please upvote!

It sounds like you used the keyboard method to trash preferences. Try the manual method to do so. It will sometimes make a difference to do a manual trashing.

To do so:

For Macintosh Users: The User Library folder in which Illustrator’s preferences are stored is hidden by default on most Macintoshes. To access it make sure that Illustrator is closed and click on the desktop to launch a Finder Window (Command-N).With this window in column view follow the path User>Home folder (it’s the folder with an icon that looks like a house—it may have the user’s name rather than “Home”) and click on the Home folder. With the Option Key pressed choose Library from the Finder Go Menu. “Library” will now appear within the Home folder. Within the Library folder find the folder called Preferences and within it find the folder called “Adobe Illustrator <Version #> Settings” (earlier versions of Illustrator might just say “Adobe Illustrator”) and the file called “com.adobe.Illustrator.plist” and delete both that folder and that file. When Illustrator is next launched it will create new preference files and the program will be restored to its defaults.

To Windows users: On Windows 7 and above the preference files are hidden. To find them go to the Control Panel and open Folder Options and then click the View tab. Then select “Show hidden files and folders” or “Show hidden files, folders or drive options” in Advanced Settings. Then delete (or rename) the folder at the end of this path: C:\Users\[User Name]\AppData\Roaming\Adobe\Adobe Illustrator [version number]\ Settings\<Language>. Make sure that Illustrator is closed when you do this. When you relaunch the program it will create new preference files and the program will be at its default settings. 

The advantage of manually deleting preference files is that after you’ve reset up the program (make sure that no document window is open) to your liking, you can create copies of your personalized “mint” preference files (make sure that you quit the program before copying them—that finalizes your customization) and use them in the future to replace any corrupt versions you may need to delete.

WHich operating system is it? If Sonoma, then maybe you did that update too early.

Apart from that: those keys definitely work on the Mac. I'm using them all the time

There might be some third party app interfering. You could start with this list:

• WebRoot
• Apple Terminal
• Word, Excel, Powerpoint
• »Enable Full Keyboard« in Settings > Accessibility > Keyboard on Mac OS
• Apple Mail, Outlook
• Spacebar is used as a shortcut by the system
• Chrome, Internet Explorer, Safari
• Wacom Desktop Center, Wacom settings
• Windows Touch Pad problem
• LastPass, Bitwarden (password managers)
• The VPN