Your prospects of finding an external solution that works reliably in Adobe products are not good. Adobe develops its flagship software to be largely independent of the governing OS. In practice that means they prefer writing their own code for things that may be run by the OS itself on one system but not on the other. A few examples of which I am aware (YMMV with another OS and Adobe versions): calling up the menu on a Mac with Ctrl+F2 and moving through them with the cursor keys does not always work, and on my Mac I cannot use Tab to navigate through all dialog box elements even though I enabled that in Preferences and it works in non-Adobe applications.
How ambidextrous are you? When I had a bout of RSI in my right arm, I found I could type with only my left hand almost as fast as wihen using just my right hand (barring the odd finger splaying key combo's -- fortunately, almost all keyboards come nowadays with left and right copies of the shift keys. I also have a piano player's spread.).
Moving the mouse efficiently with my sinister hand was more difficult, but a tip I got at the time was ... to use another mouse! The idea behind that is that a lot of mouse control is linked to muscle memory, as when you purchase a new mouse it takes some time to "switch" to its unique speed, sensitivity, and physical weight. If you transfer your daily mouse from one hand to another, your brain supposes all it has to do is mirror its usual commands, but the muscles of your arm are not used to these commands. With another mouse, your brain automatically reverts to "learning mode".
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