Hello, I believe this is a bug..When using edit in Photoshop from Lightroom with TIFF format set, none of the compression settings work. Because when the file is saved in Photoshop (ctrl+s) and comes back to Lightroom it's always an uncompressed TIFF. Every other setting works.Unfortunately I can't tell whether the fault is on Lightroom or Photoshop side..Tested on Win 7 - 64bit with LR 3.6 - 64bit and PS CS5.1 - 64bit, also on Win XP - 32bit LR 3.5, PS CS5. (In both cases camera raw version match) Lightroom 4 behaves the same.I would appreciate your replies, Thank you