Edit in> Open as smart object does not open file in Photoshop

[kennethm47177158]

Photoshop 22.4.2, Lightroom CC Classic  10.3 release, Camera Raw 13.3 Windows 10

After installing  Lightroom CC Classic and Photoshop CC 2021 twice, I am still unable to use Edit in> Open as smart object menu item to send any file from Lightroom to Photoshop although it is not grayed out.  After a long delay I get this error message in Lightroom:

"The fille could not be edited because Adobe Photoshop 2021 could not be launded."

Both programs are GPU enabled. The command worked fine until I installed the three updates for Camera Raw (1st) and Lightroom and Photoshop instaled, uninstalled and reinstalled. Now I have to open the file in Photoshop as a smart object a smar object and then edit it in Camera Raw if I wish to see my editing in Lightroom cC using the xmp file.

[GoldingD]

Are you working with Smart Previews?

[kennethm47177158]

I have  "use Smart Previews instead of originals for image editing" turned ON

[GoldingD]

I have  "use Smart Previews instead of originals for image editing" turned ON

So, then, are the originals available to LrC? Are they missing? 

see: https://www.phototraces.com/lightroom-tutorials/lightroom-smart-previews/

specifically the section "Identifying Images with Smart Previews"

[kennethm47177158 · Accepted solution]

When I ralized I could use the option Edit in > Edit in Adobe Photoshop 2021 and it exported to my copy of Photoshop correctly while not doing so with Edit in>  Open as Smart Object in Photoshop (which was not grayed out) after a very long pause producing an error message I guessed that the second command was lnot pointing to the same copy of Photoshop and may have been looking for one. So, I unplugged all of my external drives, uninstalled and reinstalled Photoshop and Lightroom again. This time both commands worked perfectly. Then I reconnected my other external hard drives.