photoshop crashes at launch running Catalina Security Update 2021-002

Same problem here! Adobe must fix this asap. What also solves it is to upgrade to Big Sur. Problem with that is that Big Sur is too resource intensive for older macs (iMac 27" 5K 4GHz i7 late 2014, even though I have 32 GB RAM), so I ended up with a clean install of Catalina and backup restore from Time Machine. Will wait with the security update 2021-002 until this is fixed.

The same issue was solved by downgrading to ver.21.2.17.

Here's a copy of the crash report.  I am running the latest version of Photoshop 2021

Process: Adobe Photoshop 2021 [1340]
Path: /Applications/Adobe Photoshop 2021/Adobe Photoshop 2021.app/Contents/MacOS/Adobe Photoshop 2021
Identifier: com.adobe.Photoshop
Version: 22.3.1 (22.3.1)
Code Type: X86-64 (Native)
Parent Process: ??? [1]
Responsible: Adobe Photoshop 2021 [1340]
User ID: 501

Date/Time: 2021-04-28 19:09:00.555 -0700
OS Version: Mac OS X 10.15.7 (19H1030)
Report Version: 12
Anonymous UUID: 8A787E2E-F4B0-DE3E-BD88-0D11A8899691

Time Awake Since Boot: 1000 seconds

System Integrity Protection: enabled

Crashed Thread: 10 GPU Sniffer Launcher

Exception Type: EXC_BAD_ACCESS (SIGSEGV)
Exception Codes: KERN_INVALID_ADDRESS at 0x00000000000004e0
Exception Note: EXC_CORPSE_NOTIFY

Termination Signal: Segmentation fault: 11
Termination Reason: Namespace SIGNAL, Code 0xb
Terminating Process: exc handler [1340]

VM Regions Near 0x4e0:
-->
__TEXT 0000000100bf5000-00000001078ad000 [108.7M] r-x/r-x SM=COW /Applications/Adobe Photoshop 2021/Adobe Photoshop 2021.app/Contents/MacOS/Adobe Photoshop 2021

Thread 0:: Dispatch queue: com.apple.main-thread
0 libsystem_kernel.dylib 0x00007fff679a1672 __getattrlist + 10
1 com.apple.CoreServicesInternal 0x00007fff46b7879c corePropertyProviderPrepareValues(__CFURL const*, __FileCache*, __CFString const* const*, void const**, long, void const*, __CFError**) + 631
2 com.apple.CoreServicesInternal 0x00007fff46b784c4 prepareValuesForBitmap(__CFURL const*, __FileCache*, _FilePropertyBitmap*, __CFError**) + 363
3 com.apple.CoreServicesInternal 0x00007fff46b82d5d _FSURLCopyResourcePropertiesForKeysInternal(__CFURL const*, __CFArray const*, void*, __CFError**, unsigned char) + 1110
4 com.apple.CoreFoundation 0x00007fff2d7c3258 CFURLCopyResourcePropertiesForKeys + 111
5 com.adobe.Photoshop 0x0000000103bce98e 0x100bf5000 + 50174350
6 com.adobe.Photoshop 0x00000001036f481d 0x100bf5000 + 45086749
7 com.adobe.Photoshop 0x00000001036f3292 0x100bf5000 + 45081234
8 com.adobe.Photoshop 0x00000001036f5238 0x100bf5000 + 45089336
9 com.adobe.Photoshop 0x0000000101f86d47 0x100bf5000 + 20520263
10 com.adobe.Photoshop 0x0000000101f871da 0x100bf5000 + 20521434
11 com.adobe.Photoshop 0x000000010362b2d5 0x100bf5000 + 44262101
12 com.adobe.Photoshop 0x00000001022901be 0x100bf5000 + 23703998
13 com.adobe.Photoshop 0x0000000102a6eefc 0x100bf5000 + 31956732
14 com.adobe.Photoshop 0x00000001037c3985 0x100bf5000 + 45934981
15 com.adobe.Photoshop 0x0000000100bf87c9 0x100bf5000 + 14281
16 libdyld.dylib 0x00007fff6785fcc9 start + 1

Thread 1:
0 libsystem_pthread.dylib 0x00007fff67a5fb68 start_wqthread + 0

Thread 2:
0 libsystem_pthread.dylib 0x00007fff67a5fb68 start_wqthread + 0

Thread 3:
0 libsystem_pthread.dylib 0x00007fff67a5fb68 start_wqthread + 0

Thread 4:
0 libsystem_pthread.dylib 0x00007fff67a5fb68 start_wqthread + 0

Thread 5:
0 libsystem_kernel.dylib 0x00007fff679a3882 __psynch_cvwait + 10
1 libsystem_pthread.dylib 0x00007fff67a64425 _pthread_cond_wait + 698
2 com.adobe.Photoshop 0x000000010374058b 0x100bf5000 + 45397387
3 com.adobe.Photoshop 0x000000010373fc8b 0x100bf5000 + 45395083
4 com.adobe.Photoshop 0x000000010373fdc2 0x100bf5000 + 45395394
5 libsystem_pthread.dylib 0x00007fff67a64109 _pthread_start + 148
6 libsystem_pthread.dylib 0x00007fff67a5fb8b thread_start + 15

Thread 6:: com.adobe.ngl-RecurringLogPosting-0x700008ffc000
0 libsystem_kernel.dylib 0x00007fff679a3882 __psynch_cvwait + 10
1 libsystem_pthread.dylib 0x00007fff67a64425 _pthread_cond_wait + 698
2 libc++.1.dylib 0x00007fff64b32623 std::__1::condition_variable::__do_timed_wait(std::__1::unique_lock<std::__1::mutex>&, std::__1::chrono::time_point<std::__1::chrono::system_clock, std::__1::chrono::duration<long long, std::__1::ratio<1l, 1000000000l> > >) + 93
3 com.adobe.Photoshop 0x000000010572a76e 0x100bf5000 + 78862190
4 com.adobe.Photoshop 0x000000010573cd07 0x100bf5000 + 78937351
5 com.adobe.Photoshop 0x000000010573cc5a 0x100bf5000 + 78937178
6 com.adobe.Photoshop 0x000000010573ce7e 0x100bf5000 + 78937726
7 libsystem_pthread.dylib 0x00007fff67a64109 _pthread_start + 148
8 libsystem_pthread.dylib 0x00007fff67a5fb8b thread_start + 15

Thread 7:
0 libsystem_pthread.dylib 0x00007fff67a5fb68 start_wqthread + 0

Thread 8:: com.adobe.ngl-0x700009102000
0 libsystem_kernel.dylib 0x00007fff679a0e4e semaphore_timedwait_trap + 10
1 libdispatch.dylib 0x00007fff67806b6b _dispatch_sema4_timedwait + 76
2 libdispatch.dylib 0x00007fff67806f97 _dispatch_semaphore_wait_slow + 58
3 com.adobe.Photoshop 0x000000010582a696 0x100bf5000 + 79910550
4 com.adobe.Photoshop 0x0000000105820e0b 0x100bf5000 + 79871499
5 com.adobe.Photoshop 0x00000001057f6db4 0x100bf5000 + 79699380
6 com.adobe.Photoshop 0x00000001057f3b98 0x100bf5000 + 79686552
7 com.adobe.Photoshop 0x00000001057f4a55 0x100bf5000 + 79690325
8 com.adobe.Photoshop 0x00000001057bc3be 0x100bf5000 + 79459262
9 com.adobe.Photoshop 0x00000001057c7f34 0x100bf5000 + 79507252
10 com.adobe.Photoshop 0x00000001057e1651 0x100bf5000 + 79611473
11 com.adobe.Photoshop 0x00000001057d69d8 0x100bf5000 + 79567320
12 com.adobe.Photoshop 0x000000010576e59e 0x100bf5000 + 79140254
13 com.adobe.Photoshop 0x0000000105711773 0x100bf5000 + 78759795
14 com.adobe.Photoshop 0x00000001057402d7 0x100bf5000 + 78951127
15 com.adobe.Photoshop 0x000000010573dd43 0x100bf5000 + 78941507
16 com.adobe.Photoshop 0x000000010573cd07 0x100bf5000 + 78937351
17 com.adobe.Photoshop 0x000000010573cc5a 0x100bf5000 + 78937178
18 com.adobe.Photoshop 0x000000010573ce7e 0x100bf5000 + 78937726
19 libsystem_pthread.dylib 0x00007fff67a64109 _pthread_start + 148
20 libsystem_pthread.dylib 0x00007fff67a5fb8b thread_start + 15

Thread 9:: VulcanMsgRecv
0 libsystem_kernel.dylib 0x00007fff679a43a6 __recvfrom + 10
1 VulcanMessage5.dylib 0x00000001149a78f0 0x114932000 + 481520
2 VulcanMessage5.dylib 0x00000001149aa854 0x114932000 + 493652
3 VulcanMessage5.dylib 0x000000011498192d 0x114932000 + 325933
4 VulcanMessage5.dylib 0x000000011497b99f 0x114932000 + 301471
5 VulcanMessage5.dylib 0x000000011497d55e 0x114932000 + 308574
6 VulcanMessage5.dylib 0x000000011497d179 0x114932000 + 307577
7 VulcanMessage5.dylib 0x00000001149832ab 0x114932000 + 332459
8 VulcanMessage5.dylib 0x0000000114982eb1 0x114932000 + 331441
9 VulcanMessage5.dylib 0x0000000114982dcd 0x114932000 + 331213
10 VulcanMessage5.dylib 0x0000000114940404 0x114932000 + 58372
11 VulcanMessage5.dylib 0x0000000114993111 0x114932000 + 397585
12 VulcanMessage5.dylib 0x00000001149b13f9 0x114932000 + 521209
13 libsystem_pthread.dylib 0x00007fff67a64109 _pthread_start + 148
14 libsystem_pthread.dylib 0x00007fff67a5fb8b thread_start + 15

Thread 10 Crashed:: GPU Sniffer Launcher
0 com.apple.AMDRadeonX4000GLDriver 0x0000000120cdd508 gldGetFenceProfilingInfo + 24
1 com.apple.opencl 0x00007fff36c98475 0x7fff36c85000 + 78965
2 com.apple.opencl 0x00007fff36cae943 clGetEventProfilingInfo + 272
3 com.adobe.Photoshop 0x000000010600f329 0x100bf5000 + 88187689
4 com.adobe.Photoshop 0x000000010600c174 0x100bf5000 + 88174964
5 com.adobe.Photoshop 0x000000010600d391 0x100bf5000 + 88179601
6 libHalideRuntime.dylib 0x000000011359b72a adobe::manta::Platform::Create(adobe::manta::EngineID const&, adobe::manta::PlatformCapabilities) + 180
7 com.adobe.Photoshop 0x00000001060161f3 0x100bf5000 + 88216051
8 com.adobe.Photoshop 0x000000010587928d 0x100bf5000 + 80233101
9 com.adobe.Photoshop 0x000000010587866f 0x100bf5000 + 80229999
10 com.adobe.Photoshop 0x0000000104e81d08 0x100bf5000 + 69782792
11 libsystem_pthread.dylib 0x00007fff67a64109 _pthread_start + 148
12 libsystem_pthread.dylib 0x00007fff67a5fb8b thread_start + 15

Thread 10 crashed with X86 Thread State (64-bit):
rax: 0x00007fd660139600 rbx: 0x0000000000000000 rcx: 0x0000000000000001 rdx: 0x0000700009184580
rdi: 0x00007fd660142600 rsi: 0x0000600003edb880 rbp: 0x0000700009184570 rsp: 0x0000700009184540
r8: 0x0000000000000001 r9: 0x0000000000000000 r10: 0x00007ffeef00aca0 r11: 0x00007fff36cae833
r12: 0x0000600003edb880 r13: 0x0000600003edb880 r14: 0x0000700009184580 r15: 0x0000700009184580
rip: 0x0000000120cdd508 rfl: 0x0000000000010202 cr2: 0x00000000000004e0

Logical CPU: 1
Error Code: 0x00000004 (no mapping for user data read)
Trap Number: 14