Program error message

When I working with Photoshop 22.1 I get a Error message often, I've heard it's because of to little memory, but I've got 16gb RAM and I use 3 external harddrives as Scratch disks. I've even heard that if you have plugins like NIK or Topaz it shows error or if you have a lot of Brushes.

Why do I get this Error messages? I have changed back to version 22.0 and it works allright.

It can not be the intention to change computers just for the program to work?