I am in Photoshop CC, 21.2.0 on a Mac running Catalina 10.15.5 (all up to date, as far as I know). Ever since moving up to my new laptop, updated Adobe CC, and Catalina in November, I have continued to have a variety of issues in all my Adobe software, including frequent crashes for no discernable reason, and the annoying greyed out selection menus (that are clickable and openable but darned hard to read).
I think one of the things that annoys me the most, as simple as it sounds, is that every commonly used Mac ap HIDES with Command > H, but some rocket scientist decided Photoshop should be Control > Command > H. . . which I always forget, and always have to look it up or use the menu. Why-oh-why is this a thing?
I also don't understand the grey selection thing, especially since it's unpredictable. Say I want to open a graphic. Maybe I created it in Photoshop, maybe I didn't. (It doesn't matter.) Sometimes I click Command > O and go the finder I want. SOME of the items (may even be a folder) will be greyed out. Some won't. (No, I am not using the "Cloud" and Yes, I have done all the "jump-through-50-hoops-to-approve-permissions thing"--more than once.) I maybe will open something and then go to open something else. DIFFERENT items may or may not be greyed out. It's not like that particular item has a permissions issue.
I don't know if anyone has any fixes for these things. Honestly, I just am hoping the next update will fix this, even though we've been through quite a few already and it has yet to abate.