Until recently when I discovered Kyle Webster's brushes for PS, I had always done my illustration and comic work in Clip Studio Paint.
I've almost completely moved back over to PS now thanks to those brushes, however, there's one feature in CSP that is keeping me there for comic work, and that's the ability to set a layer as a ref layer, which makes colouring so much easier when you set the brushes to anti-overflow as the ink doesn't go past the line art above it. If PS had this feature it would be amazing.