I don't know of a plugin that will simulate a painting. There may be an Action that will try to do this but I don't know of one. There are of course standalone programs that aim to do this.
But Photoshop offers various ways to simulate natural media. It all depends what you mean by "painting". You need to have an idea what - what style of artwork - you are aiming for. So, you can use the Art History Brush to make both loose and detailed watercolours and oils, the Mixer Brush can clone Smeary Oil brushstrokes, the Pattern Stamp Tool for detailed oils and watercolour washes, and the Smudge Tool to make highly detailed softened brushstrokes. Then there are chalks for pastels, and filters for pen and pencil outlines used in combination to produce mixed media effects like pen and wash. All of these work from a photograph.
Here is quite a nice technique using the Art History Brush:
https://www.youtube.com/watch?v=HzWpYx4rNs4://
These may involve more work than you want to put in but the results can be quite good.
David