Can't open files from desktop or USB drive

[DrGrafix]

Something bizzare is going on, probably my own doing but I'm missing something.  I'm running CS6 Photoshop and have been for a while. I can cretate new files just fine, save them just fine, and even open them (PSD or whatever) in other applications like Affinity Photo.  I can see all the files in Finder, I can even open them in preview.  But when I click on File, Open and click on either the desktop or my external USB drive, I get a popup with a giant icon but no files.  I have tried resetting PS preferences, re-starting PS, and even rebooting but no dice.  Can someone give me a clue?  Pictures show you what I get when I try to _open_ a file.  I can't even get into the folder thru PS.