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My Photoshop has always run fine. Today, it says it "could not open a scratch file because the file is locked, you do not have necessary access permissions, or another program is using the file. Use the 'properties' command in the Windows Explorer to unlock the file." I looked up other people who have had this problem, and people are saying to run the program as an admin. I did this, and PS runs, but I do not want to have to do this every time because it leads to complications in running downloaded files, and it seems that my command settings have restarted (i.e. ctrl+z only works a single time). I'm no programmer, so I have no idea how to handle the small issues.
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I had that problem also, and I don't know if you have moved your Temp file location, but for me, that was the problem.
I moved my temp file from my SSD C:\Temp to D:\Temp, and never thought about Photoshop CS6 not liking that.
I left my temp file on drive D, but changed my Enviornment setting back to C drive, and then went to the CMD (command line) as administrator, and typed in
mklink /J C:\Temp D:\Temp
And that sets up a link from my C:\Temp to my D drive for the Temp file in Windows 10.
Now Photoshop CS6 starts just as it should with no complaints, and I don't have to run it as an Administrator anymore.
Hope that helps
(I guess Adobe Photoshop only likes the C drive for it's temp file location, and this gets around that..)
Good Luck..
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