Can I delete old media cache files?

When I bought my latest PC, I had a solid state hard drive installed as my C Drive. It is only 128 Gb, but I figure it would be sufficient, since I would only use it to store programs, and no data. That is essentially what I have done.

However, in just a few short months, the free space has shrunk to about 10 Gb, and continues to shrink daily. By far the largest largest folder is

....appdata/roaming/adobe/common/media cache files/ which is about 39 Gb. THey are basically .cfa files from old and newer projects.

Can I delete these files when I am no longer actively working on the PRE 11 project?

A second question - If I uninstall/re-install PRE 11 onto a different internal drive (which I have started to do with other programs), will this folder follow it, or will the Media Cache folder still be on the C Drive?

Is there a better strategy for conserving and recovering my C Drive space?

Thanks in advance