Dante font used in manuscript … when I try to save as a pdf document in Microsoft Word whole pages change their look, with wide gaps forming between certain paragraphs or sections. This does not happen with other fonts.

That information helps.

One more question, if I may…

Exactly how are you producing the PDF file? Are you using Acrobat's “Save as Adobe PDF” or are you using Microsoft's “Save as PDF?” There is a known problem with Microsoft's PDF in that they don't embed OpenType CFF fonts and don't properly reference them for purposes of letting Acrobat or Reader use a host-based version. (I am working with Microsoft to at least fix this bug in Office 2013 - whether they will or not, who knows?)

          - Dov