When I try to open a file or create a new file in Substance Painter, it gives a critical error

Yes I did, thanks for sharing.

First of all, I have to mention that your specs are unfortunately under the minimum requirement for running Substance 3D Painter, and this can add several layers to your current issue.

I can see that the files are saved in a OneDrive application, and Substance 3D Painter doesn't support networked paths because this require an account authentification , which the software can't do.
Therefore the paths must be mapped / mounted by the operating system.

Windows : http://www.laptopmag.com/articles/map-network-drive-windows-10

Lastly your GPU seems outdated. It would be worth updating the GPU in order to see if anything changed.

Regards,

I did. Did u get it?

Hi @Etip3D,

Could you send me your log file at cdellenbach@adobe.com with a link to this thread? You'll find the log in

C:\Users\[username]\AppData\Local\Adobe\Adobe Substance 3D Painter

Let me know.