Can't Save, Save AS, or Save a copy as a jpg since updating 2/24/2025

If Photoshop, try resetting the tools and/or preferences.

To restore preferences quickly using a keyboard shortcut:

Press and hold Alt+Control+Shift (Windows) or Option+Command+Shift (Mac OS) as you start Photoshop. You are prompted to delete the current settings. The new preferences files are created the next time you start Photoshop.
Note: Using the keyboard shortcut, preference files for custom shortcuts, workspaces, and color settings will also be reset to default.

from here:

https://helpx.adobe.com/photoshop/using/preferences.html#restore_preferences

what app?

Can't export for or save for web either.