P: Slow UI when using Mac and Custom Display Profile

@Rikk Adobe RGB and sRGB monitor profiles do not fix the problem for me. What else could this be?

2013 Mac Pro, Dual AMD D700 Firepro, multiple NVME SSDs, LG 27" 4k display.

I just have to wonder why my experience that I posted 3 days ago was different from your experience. 

Mac Pro (2019)

3.3 GHz 12-Core Intel Xeon W

192 GB 2933 MHz DDR4

AMD Radeon Pro W5700X 16 GB

I have not installed LR10.1 on the stock OS that came with the machine. The new install on new partition plus migration form the old machine/Mojave is working fine though at some point when time permits I do want to do clean install of the apps I use on the clean OS partition. I will do an install of LR10.1 first to test. 

No. OS was stock. LR update was the background install through Creative Cloud.

@mac_nick Did you do a clean install of the OS and then LR10.1?

Same here. Lightroom Classic 10.1 is absolutely slow and laggy. Switching the display profile to Internet sRGB and speed is back to normal. Selecting any other profile and Lightroom is slow again.

macOS Catalina 10.15.7

Mac Pro (2019)

2,5 GHz 28-Core Intel Xeon W

96 GB 2933 MHz DDR4

AMD Radeon Pro Vega II 32 GB

Apple Pro Display XDR

I did not identify an obvious link between Lightroom performance issues and the use of eGPU. In this particular case (Library module much slower than the Develop one), the use of the internal GPU or eGPU does not seem to make any difference.

https://feedback.photoshop.com/conversations/lightroom-classic/lightroom-classic-mac-user-interface-slow-after-upgrading/5f91bbf7917fbb3a9935742e

@Rikk 

Can you link to that Office Response - I've not been able to figure out where that is - there's so many threads about this issue.

This comment might be out of date but Lightroom with an eGPU used to either not work at all or delivered terrible performance. At least a year ago, I was researching an eGPU to use with a HP 5K monitor. 

I switched my monitor profile to sRGB with v10 and I had the recollection that it more or less fixed the issue. Now, in v10.1, the Library module is again much slower to browse than the Develop module. And that's with sRGB. With a custom profile, the Library module is just unusable.

I use a MP6,1 12 cores with 64 GB RAM - catalog and photos on M.2 SSDs - using either the D500 or a VEGA 56 in an eGPU, connected to a 5K screen.