I'm 73 and if Photoshop had an independent way to enlarge the type, toolbar and side panels without using Window display settings that would be REALLY nice. Your current software enlargement settings are useless.

Jerry I am a bit older than you, and my eyesight is not flash.  It breaks my heart, but I have had to set my 4K 30 inch Asus Proart screen to 2K, _and_ have Windows display settings at 125%.  That obviously affects ALL apps, but what can you do?  It’s a bugger getting old, and that’s an end to it.

What are you using?  What screen size?

I have the big main screen, and a pair of 24 inch screens one either side, so I can have all the main panels displayed in my main workspace.  If you are not using a small screen, you don’t need the default Function key shortcuts, so I have repurposed them.  You don’t 20-20 vision to tap an F key.

Something I have just recently discovered is Configurator Reloaded which lets you create BIG buttons for whatever functions you need.  It obviously takes up a bit of screen space, but you can set it to auto show and hide.  I’ve had it less than a week and am still homing in how I want to use it, but this is how I have it set right now.  It’s not free, but thought it well worth what I paid for it.  It’s super easy to use as well.

[EDIT] Click to see the panel full size.

​@JerryDuncan Yes, unfortunately this is a 4K 3840 x 2160 display issue. I find those menu elements hard to see at times myself too. And my display is only full HD: 1920 x 1080 pixels

On a Mac I was able to set my display to a lesser percentage for the whole interface. Apple offer 5 options for this. ​@D Fosse is right that the only way seems to be to change the system settings and, thus, all apps at the same time. I guess the UX designers feel that if one app needs bigger menus, they all will. 

Frustrating I know. I wonder if Adobe could add the option as you're not the only one having this trouble

I hope this helps

neil barstow colourmanagement - adobe forum volunteer,
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Correct, Photoshop UI scaling follows the Windows setting. The idea is that what is required for one application shouldn't be different from what is required for any application. Does Photoshop behave differently in this regard to the other applications you use?

I honestly don't know what the 200% setting in Preferences is supposed to do; it does nothing here. I've assumed it's a legacy setting for older operating systems that don't support the standard scaling.