I also have this problem. It just came out of the blue on my Mac Pro 8-core. After a while Photoshop and Indesign are having issues withe the preferences file. Illustrator doesn't seem to be infected. Restarting the mac or logging out and back in does fix the problem for a while. At first I was thinking about a bad font. After intensive testing this wasn't the issue. After that I reinstalled by Mac Pro completely with only the Adobe applications. After a while I got the same issue. Next thing I was thing was een bad hard disk. I checked the HD, even bought a new one to be sure and reinstalled everything. Clean install, clean preferences. And ... the same problem. I have tried to reoccur the problem but I cannot find it. On one hand I'm glad that it's not my sole problem but on the other hand ot's really frustrating. Do you guys all use a Mac Pro? If anyone has a solution, ... Ps: I do not run spaces or use a Wacom tablet -:-)
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