Commercial use: Can I remove/edit out an object/empty frame in a stockphoto?

That's one of the reasons why stock does exist. Read carefully the licensing terms, you will need to understand, when you need an extended and when a standard licence is enough.

My unqualified opinion: The extended licence fits your application, but a standard licence could do the affair too.

Look here for more information on licensing: https://community.adobe.com/t5/stock/links-for-licensing-terms/td-p/11366788
(Disclaimer: As always with licensing, this is my interpretation of the rules. I think they are correct and advice is based on reading and interpreting the licence terms and on fair use for both the buyer and the artist/stock company, but I cannot rule out that my interpretation is wrong. I'm not an Adobe employee).

All license types allow you to modify the asset. See the comparison chart here:

https://stock.adobe.com/license-terms