After Effects loses preferences of audio-channels

Hello,

I use After Effects on macOS Sierra. My Audio-hardware is a MOTU 24 Ao (a soundcard offering 24 analogue outputs).

AE shows the MOTU 24Ao in the preferences and also all 24 channels. Due to our studio I use channels 12 and 13 for stereo-output.

Whenever I close and re-open AE again, it looses my preferences and switches back to channels 1 and 2, so I have to adjust it again.

This did not occur on macOS El Capitan or on an earlier version of AE. I re-installed the whole system 3 weeks ago.

I know this is a rare constellation of software / hardware / preferences, but maybe someone has an idea / solution nevertheless?

I found nothing in the forums.

Thanks!

Steffen (Berlin)

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MacBook Pro (late 2013)

macOS Sierra (10.12.2, latest)

AE-Version 14.0.5.1 (latest)

MOTU (Driver 2.0+71418 Firmware 1.2.8+780 - both latest)