Aligning footage in timeline with random layers

Holding down Shift while draggin a Layer Stem will snap it to pertinent points in the Timeline - this includes, Keyframes, Layer IO points, Work Area IO points and Timeline and Layer Markers. You're most likely not slowing down you dragging as you reach the desired location - if you drag too quickly, you'll pass by the snap points and being sufficiently zoomed helps; especially if there are other snap points in close proximity. 
HTH

 

Select layer 2. Press o to go to the out point of that layer. Then, hit page down to go one frame foward. Select layer 5. Press [.
Boom. Snapped.

Or, probably better, edit in Premiere Pro. It's waaaaaaaaaaaaaaaaaaaay faster than editing in AE. Then, once your clips are edited, use the Import Premiere Pro Sequence command to bring them into AE for adding your effects and motion graphics.

What I would do is just put my playhead at the beginning of Layer 2 and drag it so that Layer 5 snaps to the playhead. Additionally, the script Rift helps with layer positioning, and it's free! https://aescripts.com/rift/