If you are new to AE, please spend at least a couple of hours with the User Guide. You'll find links on this forum, the AE product page, and AE's Home Screen.
If you have successfully used rotobrush to create a matte for the pupils in your eyes then you have already poked a hole in the layer. You just have to invert the matte and then drop a white solid below the rotoscoped layer. Content-Aware Fill is the wrong tool for something like this. Depending on the shot Rotobrush may have been a very inefficient way to create the matte. I would have to see the shot and your timeline to be sure and to make any meaningful suggestions.
BTW, make sure you freeze Rotobrush when it is complete or it will start analyzing all over again and it may come up with a matte that has problems. It's a common newbie mistake.