Camera and 3D weird problems

Not sure I will be able to describe the frustrating behaviour in a comprehendible way but here goes...Everything has been working fine until I got this new 27" monitor.

Camera now is not functioning properly. If I swithch to 2 camera view the 2nd orientation window is just black. If I remove the camera after I have used it to zoom in on something the scene does revert back to how it was without the camera it will stay  at camera set location.

And when rendering out the scene I'm getting different proportions than what I'm seeing in After Effects.

This all started with the new monitor yesterday.

It's 27", 2560x1440 on Win 10 and os is scaled to 125%

Hopefully it's something obvious but am totally clued out on.

Thank you in advance