Common Plugin Stops - Works then disappears

I have been a Red Giant user for a long time. Recently, during a project, the Knoll Light factory from Universe just doesn't show anymore. Then the effect will be working where I put it and then dissappears again. 

I have contacted Red Giant and they ultimatly suggested to unplug my second monitor, which I did. Seemed to work fine for a bit, then - as it gets closer to crunch time with this proj - it started doing the above again. Now it'll show up as intended during a portion of the comp but wont show up throught out. Worked fine last week for a full day. Now this. 

All setup with 3 SSDs. One is an Nvme . Cache drives etc..

64GB ram 

2 x 1050 TI GPUs 

i7-9700 processor 

Windows 10 64 bit 

Should I delete cache completely and let it rebuild again, maybe? Hate to do that but idk what else to do.