HELP i cannot open the program

everytime i try to open after effects this message pops up (see picture)

(Una copia del progetto è stata salvata in: /Users/(USER)/Documents/After Effects Crash_11.aep.

Ultimo messaggio registrato: <9424713> <ae.blitpipe> <2> HardwareBlitpipe Engaged

Generazione del registro errori; l'operazione potrebbe richiedere alcuni minuti.)

it says i must have some problems with my preferences or plug-ins but the only way i can open after effects is by open the safe mode, in witch i cannot modify preferences nor plug-ins. what should i do? and more importantly, what did i do wrong?