How do I fix error (48::72)?

Sorry to hear about the issue.

What happens when you click on Ok? Does it allow After Effects to launch? What are your system specifications (CPU, GPU, RAM, OS version)? Is there a crash report?

Let me know.

in the future, to find the best place to post your message, use the list here, https://community.adobe.com/

p.s. i don't think the adobe website, and forums in particular, are easy to navigate, so don't spend a lot of time searching that forum list. do your best and we'll move the post (like this one has already been moved) if it helps you get responses.

<"moved from using the community bugs">