Guide layers got rendered on a couple of frames

I rendered an image sequence and in 2 out of 312 images, a guide layer got rendered into the final output.
My guess: AE uses the cache on render time..? 😬
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System info
    Application: After Effects (Beta) v18.1.0.15
    OS: Windows v10.0.19042, RAM: 63.95 GB, CPUs (logical): 24