Animate wont stop on my breakpoints - other debugging problems too

I am having problems debugging a project that a year ago I had no problem debugging. It is a flash player project with many external .AS files.

Currently I am using Animate 22.0.5 build 191.  I am trying to debug this Adobe Flash project..  Under Publish Settings -> Flash .SWF -> advanced I have added the checkbox for "Permit Debugging"

When I set breakpoints in the main constructor in the .AS file, and then do Debug -> Debug to launch the project, Animate does not stop at the breakpoints. I have put trace() statements in the code just after the breakpoints, and trace statements are sending their messages to the log Output. 

Yesterday I was getting TypeError #1009 for null pointer access. Single stepping code would work. But a debug continue would not hit later breakpoints.

I thought last night I was getting some breakpoints to trigger. But I noticed that when I stepped into routines, then did continue, breakpoints at higher levels of the code were not hit.  Today, I cant get any breakpoints to trigger, except for null exception.

I also notice that a divide by zero I purposefully put in the code is being ignored, no exception generated, the trace statement just past the divide sends output to the log.