On Friday I was able to use camera raw inside bridge and PS, today I cannot turn on GPU ACCELERATION. I have an NVIDIA rtx 5080, and should have zero issues. I need a fix. Please.

You might read through this article:

https://helpx.adobe.com/uk/camera-raw/kb/acr-gpu-faq.html#troubleshoot-acr

The section entitled "GPU troubleshooting steps for Camera Raw and Lightroom" is relevant. In that section, subsection 7 is worth investigation as I know that the presence of the files TempDisableGPU3 or TempDisableGPU2 have been an issue for many users.

How are you trying to turn on GPU acceleration and what happens when you do? Which CPU do you have and does it have onboard graphics? If so, disable it in Device Manager.