Click and Drag not working (InDesign, Illustrator, Photoshop)

I can start a project in any of the three programs (In, AI, PS) I can create shapes, content boxes, or insert a photo and click and drag it into place at the scale I want.

However when I try to resize it after the original placement it will not resize. I can move things with the arow keys, I can select corners and click and drag to select things, I just can not move the items once I click them. Sometimes, It will also work for one or two click and drags and then stop working again.

I have rename the Adobe Illustrator XX folders.

I have uninstalled and reinstalled. New and older versions.

I have deleted previous versions and all the folders in my system.

I have tried closing all other apps and only running one of these programs at a time.

This is a recent thing, within the past month on my PC.  It works on my Desktop, something changed in the last month when I installed the latest update and it will not revert to the previous version.

Please help,