Adobe Digital Editions is not starting

This morning ADE 4.5.11 did not start on my work computer. Yesterday it was running fine on Windows 10. I've tried uninstalling, reinstalling, downloading with another browser and restarting my computer. Task Manager shows that the program starts, but it closes down within a few seconds without an error message. I use this a lot for my work and personal studies, and I cannot afford it not to work.