Digital Editions in domain with roaming profiles

I asked back on April 22, but had no replies.  Will Digital Editions work for users in a domain with roaming profiles?  By "work" I mean, when a user logs into a domain computer, configures and uses DE, and then logs out, will the next domain computer they log into have the configuration and checked out books that the user had on the first computer?

Please let me know if you need additional information to clarify the question.

Thank you,

Michael Davidson