Does the original Nook work with Digital Editions 4.5 whatever?

Just bought a new Windows 10 computer.  Downloaded the latest Digial Editions and then a book in EPUB format.  Transfered it to my Nook, but it will not open on the Nook.  The Nook says the book is no longer available and has been returned.  Was able to download the book, transfer to Nook and open successfully using my old computer running Digital Editions 3.  Anyone know if 4.5 will work with the original Nooks and if not, where I can get a 3.0 Digital Editions download?