is adobe 4.5 compatable with windows 10

I have downloaded (and re-downloaded) adobe 4.5 for windows 10 but when I run the compability check it will only give me choices for windows 8 and lower.  Does that mean it won't run with windows 10? I have been trying for some time to get overdrive to download to my computer through ADE - that works but won't transfer to my kobo.  Is there some issue with ADE 4.5 and windows 10?