Creative Cloud Desktop App Update Error - Error code 146
I am getting the following error when trying to update the CC Desktop App. I have followed the link to learn about error 146, and viewed the log file. (log file info below)

The log file output shows the following:
FATAL: Error (Code = 146) executing in command 'MoveDirectoryCommand' for package: 'CoreSync-mul', version:2.4.2.61
FATAL: Error occurred in install of package (Name: CoreSync-mul Version: 2.4.2.61). Error code: '146'
WARN: Failed to move directory '/.adobeTemp/2BA46992-11BE-4890-9553-00CFF1E777F9/1/CoreSync' to '/System/Library/Perl/Extras/5.18/darwin-thread-multi-2level/DBI/DBD/SqlEngine/CoreSync'
The Adobe support team have suggested it's to do with permissions - but I have never had an issue before, nor have I changed any permissions. I am logged in as an admin. Any ideas what to do next ?